ESF-EMBO Symposium
Cell Polarity and Membrane Traffic
31 March - 5 April 2012
Final Programme |
| SATURDAY 31 March |
17:00 onwards: Registration at the ESF-RC desk
19:00: Dinner
20:00 - 21:00: Introduction by Keith Mostov
Keynote Abcam Lecture: Daniel St Johnston (Gurdon Institute, Cambridge, UK)
Nuclear movement and the polarisation of the Drosophila oocyte
21:00: Welcome drinks
| SUNDAY 1 April |
08:45 - 09:00: OPENING WORDS: Catherine Rabouille and Keith Mostov
Session 1: Epithelial morphogenesis, polarized membrane and mechanics
Chair: Alejo Rodriguez-Fraticelli, Centre of molecular biology Severo Ochoa, Spain
09:00 - 09:40: Keith Mostov, University of California School of Medicine, USA
Homeostasis and regeneration of epithelial structures in 3 dimensions
09:40-10:20: Fernando Belmonte, Centro de Biología Molecular Severo Ochoa CSIC, Spain
Molecular mechanisms of apical lumen formation in epithelia
10:20-10:40: Antoine Guichet, Institut Jacques Monod, France
PI(4,5)P2 sustained by the PIP5K Skittles controls the organisation of columnar epithelia through the membrane targeting of Bazooka/PAR-3 in Drosophila
10:40-11:10: Coffee break & Group Photo
11:10-11:30: Martin Gloerich, Stanford University, USA
Linking intestinal cell polarity to brush border formation
11.30-12:10: Thomas Lecuit, University de la Mediterranee, France
Regulation of cell mechanics during morphogenesis
12:10-12:30: Catherine Qiurong Pan, Mechanobiology Institute, Singapore
BPGAP1 Coordinates Rho and Cortactin for Cell Polarity and Cell Invasion Through MEK2 And Pin1
12.30-14.00: Lunch
16.00-16.30: Coffee break
Session 2: Cell migration and epithelial morphogenesis
Chair: Anjana Narayanan, Baylor College of Medicine, USA
16.30-17.10: Sandrine Etienne-Manneville, Institut Pasteur, France
Cadherin dynamics during collective directed migration
17.10-17.30: Hesso Farhan, University of Konstanz, Switzerland
Signaling at the Golgi in cell migration
17:30-18:10: Michel Labouesse, IGBMC, France
A pathway for unicellular tube extension
18:10-18:30: Gregoire Michaux, Institut de Genetique et Developpement de Rennes, France
Control of apical sorting and polarity maintenance during epithelial morphogenesis in c.elegans
18.30: Dinner
20.00-21.30: Poster session 1
| MONDAY 2 April |
Session 3: Endocytosis
Chair: Jean Baptiste Manneville, Institut Curie, France
09.00-09.40: Anne Spang, Biocenter, Switzerland
Regulation of early-to-late endosomal transport
09.40-10.20: Enrique Rodriguez Boulan, Weill Cornell Medical College, USA
Trafficking of plasma membrane Protein in AP-1B(+) and AP-1B(-) epithelia
10:20-10:50: Coffee
10:50-11:30: Thomas Vaccari, IFOM, Italy
Vesicle sorting at endosomes: a gateway to signaling, polarity and degradation
11:30-12:10: Marta Miaczynska, International Institute of Molecular and Cell Biology, Poland
The role of endocytic proteins in signaling and transcriptional regulation
12:10-12:30: Marko Brankatschk, Max Planck Institute for Molecular Cell Biology, Germany
A new Rab library in Drosophila
12.30-14.30: Lunch
16.00-16.30: Coffee break
Session 4: Endocytosis and asymmetric cell division
Chair: Aniko Keller-Pinter, University of Szeged, Hungary
16:30-17:10: Jurgen Knoblich, Institute of Molecular Biotechnology, Austria
Asymmetric cell division in neural stem cell lineages
17:10-17:50: Marcos Gonzalez-Gaitan, University of Geneva, Switzerland
Sara endosomes during asymmetric cell division
17:50-18:10: Roland Le Borgne, Institut de Genetique et Developpement de Rennes, France
Septins are required for the establishment of adherens junctions at the exit of mitosis of polarized cells
18:10-18:30: Franz Meitinger, DKFZ-ZMBH alliance, Germany
The NAN complex regulates Rho1 and Cdc42 at the cell division site
18:30-20:00: Dinner
20:00-21:30: Poster session 2
| TUESDAY 3 April |
Session 5: Epithelial morphogenesis and junctional protein trafficking
Chair: Sven van Ijzderdoorn, University Medical Centre Groningen, The Netherlands
09.00-09.40: Catherine Rabouille/ Adam Grieve, The Hubrecht Institute, The Netherlands
Role of GRASP65 in epithelial polarity
9:40-10:20: Ian Macara, University of Virginia, USA
The Scribble polarity protein blocks retromer-mediated retrieval of E-cadherin to the Golgi
10:20-10.40: Sarah Fletcher, University of Birmingham, UK
Internalization of occludin and its role in the regulation of epithelial cell migration
10.40-11.10: Coffee break
Session 6: Structure, modeling, tools
Chair: Mathias Weiss, University of Bayreuth, Germany
11.10-11:50: Karin Reinisch, Yale University, USA
Activation of Rab GTPases
11:50-12:10: Kiran Kulkarni, Institute of Cancer Research, UK
On the mechanism and specificity of DOCK guanine nucleotide exchange factors
12:10-12:30: Franck Perez, Institut Curie, France
Cargo Partitioning in the secretory pathway imaged using synchronized trafficking
12.30: Lunch
14.00: Free Time
18:15: Dinner
Session 7: Stem cells and polarity
Chair: Alfredo Caceres, Institute Mercedes and Martin Ferreyra, CONICET, Argentina
19.30-20:10: Andrea Brand, The Gurdon Institute, UK
Stem cells to synapses: regulation of self-renewal and differentiation in the nervous system
20:10-20:50: Helena Richardson, Peter MacCallum Cancer Centre, Australia
The apical-basal polarity regulators, Lgl and aPKC, in the regulation of signaling pathways through protein trafficking
20:50-21:10: Hernan Lopez-Schier, Center for Genomic Regulation, Spain
Compartmentalized signaling and epithelial mirror symmetry
21:10-21:30: Matias Simons, Center for System Biology, Germany
Flamingo controls membrane trafficking during epithelial morphogenesis via the (pro)renin receptor
| WEDNESDAY 4 April |
Session 8: Polarity and disease/cilia
Chair: Julia Gross, German Center Research Center, Germany
09.00-09.40: Peter Jackson, Genentech, USA
Trafficking Membrane Proteins to Primary Cilia
09.40-10.20: Ben Margolis, University of Michigan, USA
The Ran Importin System in Cilia Trafficking
10.20-10:50: Coffee break
10:50-11.30: Inke Nathke, University of Dundee, UK
Changes in cell and tissue architecture in early colorectal cancer
11:30-11:50: Barry Thompson, Cancer Research UK, UK
Self recruitment of apical polarity determinants via regulated trafficking of Crumbs
11:50-12:10: Sandra Iden, University of Cologne, Germany
Tumor type-dependent function of the Par3 polarity protein in skin tumorigenesis
12:10-12:30: Roman Polishchuk, Telethon Institute of Genetics and Medicine, Italy
New insight in trafficking of Wilson and Menkes disease proteins
12.30-14.00: Lunch
15.30-16.00: Coffee break
Session 9: Polarity in plants and in immunology
Chair: Lukas Langowski, University of Gent, Belgium
16.00-16.20: Pankaj Dhonukshe, Utrecht University, the Netherlands
Mechanistic framework for establishment, maintenance and alteration of cell polarity in plants
16:20-16:40: Viktor Zarsky, Charles University and Inst. of Exp. Botany ASCR, Czech Republic
Exocyst functions in cell polarity regulation in plants
16:40-17:00: Maria-Isabel Yuseff, Institute Curie, France
Polarised secretion of lysosomes at the B cell synapse couples antigene extraction to processing and presentation
17:00-17:10: Dwijendra Gupta, University of Allahabad, India
Nanophosphors: Preparation, Characterization studies, Isolation of Biological membranes and potential Role in Drug Delivery
17:15-18:15: Introduction by Catherine Rabouille
Special lecture: Marino Zerial, Max Planck Institute for Molecular Cell Biology, Germany
Multi-scale analysis of endosome biogenesis, hepatocellular polarity and metabolism in mouse liver
18:15-19:00: Forward Look Plenary Discussion.
Choice of the chairs for next meeting
19.00: Get-together & Conference Dinner
| THURSDAY 5 April |
Breakfast and departure
Partnership
This conference is organised by the European Science Foundation (ESF) in partnership with the European Molecular Biology Organization (EMBO).
