Development of Methods to Investigate the Interaction between Nutritional, Environmental and Genetic Factors in Early Human Development: demonstration project on orofacial clefts (1998-2001)

Project Number

Convenors

co-chaired by Dr. Peter A. Mossey
(University of Dundee Dental School, UK)

and by
Dr. Ségolène Aymé
(INSERM, Villejuif, France)

Abstract

Orofacial clefting is one of the commonest human birth defects occurring in about one in 700 babies. Recent evidence that appropriate nutrition and environmental conditions can reduce the incidence of orofacial clefting provides one avenue for future research. Equally important is the genetic side with the ongoing search for candidate genes. The network will provide a forum to identify the most fruitful research strategies in these areas and the interaction between the two.

Duration

3 years, from June 1998 to December 2001.