ESF Research Conferences

17:00–19:30

Registration at the ESF Desk                                                                                           

19.30

Welcome Drink

20.00

Dinner

08.45-09.00

Conference Opening and Welcome Message from the Chair, Joris Messens

09.00-09.40

Bob Buchanan, University of California, US
Thioredoxin and Redox Regulation Reach Out to the Third Domain of Life

Session I -  Redox signaling and regulation
Chair:  Elias Arnér, Karolinska Institutet, SE

09.40-10.20

Jonathan Stamler, Institute for Transformative Molecular Medicine, Case Western Reserve University and University Hospitals, US
Paradigms for Protein S-nitrosylation and Denitrosylation     

10.20-10.40

Katarina Johansson, Karolinska Institutet, SE
Expanding the Knowledge of Redox Regulation - Development of Tools to Simultaneously Determine Key Transcription Factor Activities in Individual Cells

10.40-11.00

Coffee break

11.00-11.40

Sue Goo Rhee, Ewha Womans University , KR
Intracellular Messenger Function of Hydrogen Peroxide and Its Regulation via Peroxiredoxin

11.40-12.20

Stuart Lipton, Sanford|Burnham Medical Research Institute, US
Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death

12.20 -12.40

Aeid Igbaria, CEA Saclay, FR
The function of glutathione in eukaryotic cells and its cellular compartmentation

13:00 -15:00

Lunch

15.00-17.00

Poster session with Coffee 

Session II – Antioxidants defense by low molecular weight thiols
Chair: Katja Becker, Giessen University, DE

17.00-17.40

Luise Krauth-Siegel, Universität Heidelberg, DE
Hydroperoxide detoxification in the unique trypanothione metabolism of African trypanosomes

17.40-18.20

Alfonso Pompella, University of Pisa, IT
Cellular and soluble gamma-glutamyltransferase: glutathione, thiols and beyond

18.20-18.40

Koen Van Laer, Brussels Center for Redox Biology, VIB-VUB, BE
The mycoredoxin-1 defense mechanism against oxidative stress in Mycobacterium tuberculosis

18.40-19.00

Chris Hamilton, University of East Anglia, UK
The chemical thiology of bacillithiol: An unique biothiol in B. anthracis, B. cereus, S. aureus and other Low G+C Gram positive bacteria

19:15 - 21:00 

Dinner

21:00 - 23:00

Poster session and open bar

Session III – Thiol-based catalysis and oxidative stress
Chair: Joris Messens, VIB Department Structural Biology, BE

09.00-09.40  

Leslie Poole, Wake Forest School of Medicine, US
Investigation of biologically-relevant protein oxidation

10:00–10:30   

Coffee Breakand Group Picture

09.40-10.20

Lars Hederstedt, Lund University, SE
Extracytoplasmic protein disulfide bond management in the Gram-positive bacterium Bacillus subtilis

10.20-10.40  

Kostas Tokatlidis, Institute of Molecular Biology and Biotechnology, GR
Chaperone-induced folding, a novel targeting signal and substrate mimicry control redox trapping and recycling in mitochondria

10:40–11:00

Coffee Break ad Group Photo       

11.00-11.40

Ursula Jakob,  University of Michigan, US   
Oxidative Stress and Redox Regulation

11.40-12.00

Katleen Denoncin, Brussels Center for Redox Biology, de Duve Institute, WELBIO-UCL, BE
Redox regulation of the periplasmic L-arabinose binding protein

12.00-12.20

Ester Zito, University of Cambridge, UK
Redundancy of disulfide oxidases in mammals

12:30 - 14:30

Lunch

15.00-17.00

Poster session with Coffee

Session IV: Iron sulfur and Thiol conjugates
Chair: Roland Lill, Philipps Universität Marburg, DE

17.00-17.40 

Christopher Lillig, University Marburg, DE
Glutaredoxins at the intersection of redox regulation and iron homeostasis

17.40-18.20

Nicolas Rouhier, Nancy University, FR
Investigating redox- and iron-sulfur cluster-related functions of plant monothiol glutaredoxins

18.20-18.40

Carsten Berndt, Karolinska Institute, SE
The role of dithiol Glutaredoxins during embryonic development and differentiation

18.40-19.00 

Caryn Outten, University of South Carolina, US
Sensing and Regulating Intracellular Iron Using GSH and Fe-S Clusters

19:15 - 21:00 

Dinner

21:00 - 23:00

Poster session and open bar

Session V – Redox Structural Biology
Chair: Leslie Poole, Wake Forest School of Medicine, US

09.00-09.40

Jenny Martin, University of Queensland, AU
Targeting bacterial redox proteins to develop compounds with antivirulence  activity

09.40-10.20

Todd Lowther, Wake Forest School of Medicine, US
Molecular mechanism of the repair of hyperoxidized peroxiredoxins by sulfiredoxin

10.20-10.40   

Kenji Inaba, Kyushu University, JP
Structure and mechanism of the protein disulfide formation systems in human cells

10:40-11:00

Coffee break

Session VI – Folding
Chair: Johannes Herrmann, University of Kaiserslautern, DE

11.00-11.40

Agnieska Chacinska, International Institute of Molecular and Cell Biology, PL
Disulfide bond formation in mitochondria – nothing by chance

11.40-12.20       

Neil Bulleid, University of Glasgow, UK
Lecture to be announced

12.20-12.40   

Jan Riemer, University of Kaiserslautern, DE
Oxidative folding in mitochondria of mammalian cells

13:00 

Lunch

15:00       

Excursion

19:30

Get together Drink and Conference Dinner

Thursday 8 September

Session VII – Redoxins
Chair: John Mieyal, Case Western Reserve University, US

09.00-09.40       

Sabine Zachgo, University of Osnabrück, DE
ROXYs: glutaredoxins and flower development

09.40-10.20

Junji Yodoi, Kyoto University, JP
Anti-Inflammatory redox regulation  by Redoxisome with  thioredoxin/TRX and TBP-2/TXNIP/VDUP-1

10.20-10.40

Elizabeth Veal, Newcastle University, UK
Responding to stress; peroxiredoxins as regulators of stress responses and ageing

10.40-11.00    

Coffee break

Session VIII Redox Technologies
Chair: Lars Leichert, Ruhr-University Bochum, DE

11.00-11.40   

Kate Carroll, The Scripps Research Institute, US
Painting the Cysteine Chapel: New Tools to Probe Oxidat

11.40-12.20       

Merridee Wouters, Deakin University, AU
Identifying components of thiol-based signalling pathways: computational approaches

12.20-12.40       

Pablo Martinez-Acedo, CBMSO - CSIC/UAM, ES
GELSILOX: simultaneous high-throughput identification and quantification of thiol redox state and total proteomes

13:00   

Lunch

15.00-17.00 

Poster session with Coffee

Forward Look
Chair: Arne Holmgren, Karolinska Institute, SE

17.00-17.20   

Karl Josef Dietz, University of Bielefeld, DE
The chloroplast 2-Cys peroxiredoxin as a redox regulatory hub in the chloroplast

17.20-18.20   

Frederico Pallardo, University of Valencia, ES
Role of nuclear glutathione in the control of cell

18.20-19.20       

Leopold Flohé, Otto-von Guericke-Universität Magdeburg, DE
Changing paradigms in thiol redoxology

19:30 - 21:00 

Dinner

21:00 - 23:00

Poster session and open bar