329 Final Programme

ESF-UB Conference in Biomedicine

Nanomedicine: Reality Now and Soon

23-28 October 2010

Final Programme

Saturday 23 October

17:00 - 19:00

Registration at ESF Desk

19:00 - 21:00

Welcome Drink and Dinner

Session 1: Setting the Scene
Chair: Gert Storm - Utrecht University, NL

21:00 - 21:15

Gert Storm - Utrecht University, NL
Opening Address

21:15 - 21:45

Ruth Duncan - Cardiff, UK
Nanomedicines: from lab to clinical practice, successes, challenges and future opportunities

21:45 - 22:30

Mauro Giacca, International Centre for Genetic Engineering and Biotechnology, IT
Gene transfer in cardiovascular medicine   

Sunday 24 October

Session 2: Advanced Nanomaterials and Bioanalytics I
Chair: Fernando Palacio - CSIC - University of Zaragoza, ES

08:30 -  09:20

Kostas Kostarelos - University of London, UK
Carbon-based nanomaterials   

09:20 - 10:10

Heinrich Hofmann - EPFL, CH
Magnetic nanoparticles/QDs   

10:10 - 10:40

Coffee Break

10:40 - 11:30

Martin Bennink - University of Twente, NL
Nanotechnological tools to study biomolecular interactions on the single molecular scale   

11:30 - 12:20

Chrit Moonen - University Victor Segalen Bordeaux, FR
Triggered release/ultrasound    

12:20 - 12:35

Khuloud Al-Jamal - University of London, UK
Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing
(short talk)

12:35 - 12:50

Angel Millan - University of Zaragoza, ES
Multifunctional nanoplatform for in vivo and in vitro biomedical applications
(short talk)

12:50 - 13:05

Raymond Schiffelers - Utrecht University, NL
Nanobodies as new targeting ligands
(short talk)

13:05

Lunch

Special Guest Lecture
Chair: Gert Storm - Utrecht University, NL

15:15 - 15:45

Coffee Break

15:45 - 16:45

Huub Schellekens - Utrecht University, NL
Developing nanomedicines while pharmaceutical innovation is in serious crisis

16:45 - 17:00

Beat Löffler - European Foundation for Clinical Nanomedicine, CH
Update on the landscape of major european nanomedicine organizations

17:00 - 17:50

Poster Session I

Session 3: Advanced Nanomaterials and Bioanalytics II
Chair: Manuel Fuentes - University of Salamanca, ES

17:50 - 18:40

Joshua LaBaer - Arizona State University, US
Nanobiosensors   

18:40 - 18:55

Muhammad Asif - Linköping University, SE
Potentiometric measurements by using zinc oxide nanorods/nanowires to characterize a single cell
(short talk)

18:55 - 20:15

Dinner

20:15 - 21:05

Bing Song - Cardiff University, UK
Nanomaterials to direct stem cell migration/differentiation in neuronal injury  

21:05 - 21:20

Maria Gonzalez Gonzalez - Universidad de Salamanca, ES
Identification of biomarkers in colorectal cancer (pre- & post-chemotherapy) by nucleic acids programmable protein microarrays (nappa), ifish and SNPs approaches
(short talk)

21:20 - 21:35

Ivan Liashkovich - University of Münster, DE
Novel method of controlled and inducible AFM tip functionalisation with biomolecules
(short talk)

21:35 - 21:50

Nasrin Lotfibakhshaiesh - Imperial College London, UK
Nanostructure Strontium- substituted Bioactive Glass Coatings for Medical Implants
(short talk)

21:50 - 22:05

Kishore Paknikar - Agharkar Research Institute, IN
Biostabilized silver nanoparticle based topical antimicrobial gel formulation for the treatment of burns, wounds and diabetic ulcers
(short talk)

Monday 25 October

Session 4: Nanopharmaceuticals on the market
Chair: Rogerio Gaspar - University of Lisbon, PT

08:30 – 09:20

Francesco Veronese - University of Padua, IT
Impact of PEG-proteins   

09:20 - 10:10

Felix Kratz - University of Freiburg, DE
Albumin, a carrier for nanomedicine   

10:10 - 10:20

Group Photo

10:20 – 10:50

Coffee Break

10:50 - 11:40

Alberto Gabizon - University of Jerusalem, IL
Impact of Doxil/Caelyx   

11:40 - 11:55

Ahmad Arouri - University of Southern Denmark, DK
sPLA2-susceptible anticancer double lipid prodrugs
(short talk)

11:55 - 12:10

Catharina Davies - Norwegian University of Science and Technology, NO
The impact of ultrasound on liposomal drug release
(short talk)

12:10 - 12:25

Elaine Ferguson - Cardiff University, UK
Novel antimicrobial polymer conjugates designed to treat Gram-negative infections and circumvent toxicity and resistance
(short talk)

12:25 - 12:40

Camilla Foged - University of Copenhagen, DK
Immunity by formulation design: Customizing the adjuvant properties of cationic liposomes by rational combination with immunopotentiators
(short talk)

12:40 - 12:55

Stephen Hart - University College London, UK
Integrin-Targeted, Smart Nanocomplexes for Tumour Specific Delivery and Therapy by Systemic Administration
(short talk)

12:55 - 13:10

Huw Summers - Swansea University, UK
Stochastic nanoparticle dose delivery and dilution in proliferating cell populations
(short talk)

13:10

Lunch

Session 5: NanoImaging
Chair: Ruth Duncan - Cardiff, UK

15:30 - 16:00

Coffee break

16:00 - 17:00

Poster Session II

17:00 - 17:50

Holger Gruell - Philips Research, NL
Nanocarriers for molecular imaging and therapy

17:50 - 18:40

Enzo Terreno - Università degli studi di Torino, IT
Imaging-guided drug delivery  

Session 6: Interactions with the biological milieu I
Chair: Hans Oberleithner, University of Muenster, DE

18:40 - 18:55

Chiara Callies - Westfälische Wilhelms Universität Münster, DE
Membrane potential depolarization softens vascular endothelial cells
(short talk)

18:55 - 19:10

Johannes Fels - Universität Münster, DE
Nanomechanics of vascular endothelial cells studied with a hybrid fluorescence atomic force microscope
(short talk)

19:10 - 20:30

Dinner

20:30 - 21:20

Dusica Maysinger - McGill University, CA
Intracellular targeting/trafficking/processing   

Round table I  
Chair: Fernando Palacio - CSIC, University of Zaragoza, ES

21:20 - 22:20

Developing nanomaterials for biomedical applications: problems and pitfalls
With: Carlos Buesa - Oryzon Genomics, ES

Tuesday 26 October

Session 7: Interactions with the biological milieu II
Chair: Manuel Fuentes - University of Salamanca, ES

09:00 - 09:50

Moein Moghimi - University of Copenhagen, DK
Immunogenicity, opsonization, complement activation, pharmacokinetics 

09:50 - 10:30

Coffee Break

Session 8: Ligand-mediated targeting
Chair: Gert Storm - Utrecht University, NL

10:30 - 11:20

Terry Allen, University of Alberta, CA
Ligand-targeted nanomedicines

11:20 - 11:35

Anna Roig - Institut de Ciencia de Materials de Barcelona, ES
Magnetic-silica nanospheres. Application as contrast agents for MRI and as drug delivery carriers
(short talk)

11:35 - 11:50

Suna Erdogan - Hacettepe University, TR
Iopromide and Tc-99m loaded nano-sized tumor targeted liposomes for tumor imaging by spect/ct
(short talk)

Session 9: Nanopharmaceuticals in clinical development
Chair: Ruth Duncan - Cardiff, UK

12:00 - 12:30

Terry Allen - University of Alberta, CA
Advances in siRNA-based therapeutics

12:30

Lunch

15:30 - 16:00

Coffee Break

16:00 - 17:00

Poster Session III

17:00 - 17:50

Maria Jesus Vicent - Centro de Investigación Príncipe Felipe, ES
Polymeric drug conjugates   

17:50 - 18:05

Josbert Metselaar - Enceladus Pharmaceuticals BV, NL
Independent short communication: Nanocort   

18:05 - 18:55

Terry Allen, University of Alberta, CA
New anticancer formulations   

18:55 - 20:15

Dinner  

Session 10: Targeted Nanomedicine & EC
Chair: Gert Storm - Utrecht University, NL

20:15 - 20:30

Gert Storm - Utrecht University, NL
Introduction Integrated Project (FP6) MediTrans/Liposomal dexamethasone - cancer 
(short talk) 

20:30 - 20:45

Cristianne Rijcken, Utrecht University, NL
Polymeric micelles - cancer   
(short talk)

20:45 - 21:00

Alessandro Maiocchi - Bracco Imaging SpA, IT
Gd-liposomes - imaging     
(short talk) 

21:00 - 21:15

Xandra Lie
Commercial and technological comparison of industrial nanomedicines
(short talk)

Round table II
Chair: David Thomas, University of Cardiff, UK

21:15 - 22:20

From the laboratory to the patent and then to the patient: managing the process of research translation
With: Arne Dessen - AlgiPharma AS, NO

Wednesday 27 October

Session 11: Intracellular delivery of macromolecules
Chair: Stefaan De Smedt - Ghent University, BE

08:30 - 09:20

Victor Shahin - University of Muenster, DE
Structure and function of the nuclear barrier   

09:20 - 10:10

Stefaan De Smedt - University of Ghent, BE
Plasmid transfer to the nucleus

10:10 - 10:40

Coffee break

10:40 - 11:30

Wim Jiskoot - Leiden University, NL
Vaccins   

Session 12: Tissue repair
Chair: David Thomas, University of Cardiff, UK

11:30 - 11:50

David Thomas - Cardiff University, UK
Repair and remodeling: the clinical problem   

11:50 - 12:40

Viola Vogel - ETH, CH
Nanoscale scale analysis of cellular movement   

12:40 - 13:30

Giuseppe Battaglia - University of Sheffield, UK
Getting inside mammalian cells: from effective therapy to single cell diagnostics

13:30

Lunch

15:30 - 16:00

Business Meeting - Forward Look

16:00 - 16:30

Coffee Break

16:30 - 17:50

Poster Session IV 

Session 13: Closing the scene
Chair: Hans Oberleithner, University of Muenster, DE

17:50 - 18:40

Mathias Brust - University of Liverpool, UK
Gold nanoparticles

18:40 - 19:30

Rogerio Gaspar - University of Lisbon, PT
Regulatory/ethical/societal aspects   

20:00

Conference Dinner

Thursday 28 October

08:00

Breakfast and Departure

With support from: